Pulmonary hypertension with unclear or multifactorial etiologies

Group 5 of WHO classification

 Hematologic disorders 

• myeloproliferative disorders

• chronic haemolytic anaemia

• Splenectomy 

 Systemic disorders 

• vasculitis

• sarcoidosis

• pulmonary Langerhans cell histiocytosis

• lymphangioleiomyomatosis

• neurofibromatosis

 Metabolic disorders 

• glycogen storage disease

• Gaucher disease

• thyroid disorders

miscellaneous conditions

• tumor obstruction

• Segmental pulmonary hypertension

• mediastinal fibrosis

• chronic renal failure on dialysis

Sources

1. Clinical features and diagnosis of pulmonary hypertension of unclear etiology in adults https://www.uptodate.com/contents/clinical-features-and-diagnosis-of-pulmonary-hypertension-of-unclear-etiology-in-adults?search=%20pulmonary%20hypertension&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

2. Pulmonary Arterial Hypertension    https://emedicine.medscape.com/article/303098-overview